HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Water → 1-(2-Amino-2-methylpropoxy)-2,2,5,5-tetramethylcyclopentane
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Water | HCID 962 | — |
| Edukt | Potassium Hydroxide | HCID 14797 | — |
| Edukt | N-Boc-1-(2-amino-2-methylpropoxy)-2,2,5,5-tetramethyl cyclopentane | HCID 20165736 | — |
| Lösungsmittel | Trifluoroacetic acid | HCID 6422 | — |
| Produkt | 1-(2-Amino-2-methylpropoxy)-2,2,5,5-tetramethylcyclopentane | HCID 20165755 | — |
Reaktionsschritte
N-Boc-1-(2-amino-2-methylpropoxy)-2,2,5,5-tetramethyl cyclopentane is dissolved in trifluoroacetic acid and stirred overnight. The solution is poured into water and neutralized with 20% aqueous KOH. The mixture is extracted with ethyl acetate, dried over MgSO4, filtered and evaporated to give 1-(2-amino-2-methylpropoxy)-2,2,5,5-tetramethylcyclopentane.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04698231 |
| Quelldatensatz | uspto-grants-1987_10 |
| ORD ID | ord-1a1f9a151e464812b3c202bdce184c17 |
| Quellennotiz | uspto-grants-1987_10 |