4-chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline → 1-Isobutyl-4-methoxy-1H-imidazo[4,5-c]quinoline

Beteiligte Stoffe

Reaktionsschritte

Using the method of Example 157, 4-chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline (from Example 96) was reacted with sodium methoxide to provide 1-isobutyl-4-methoxy-1H-imidazo[4,5-c]quinoline, melting point 111°-114° C. after sequential recrystallizations from aqueous ethanol and diethyl ether. Analysis: Calculated for C15H17N3O: %C, 70.6; %H, 6.7; %N, 16.5; Found: %C, 70.6; %H, 6.7; %N, 16.5.

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