n-Methyl-3-nitropyridin-4-amine → 4-N-methylpyridine-3,4-diamine

HRID 257415

Reaktionsgleichung

Reaktionsgleichung von HRID 257415
[N+:1]([C:4]1[CH:5]=[N:6][CH:7]=[CH:8][C:9]=1[NH:10][CH3:11])([O-])=O>C(O)C.[Pt]=O>[NH2:1][C:4]1[CH:5]=[N:6][CH:7]=[CH:8][C:9]=1[NH:10][CH3:11]

Komponenten

4

Edukt 1

HCID 556016n-Methyl-3-nitropyridin-4-amine

Produkt 1

HCID 9104124-N-methylpyridine-3,4-diamineAusbeute 80 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 82844Platinum oxide (PtO)KatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

150 mg of platinum oxide was added to 10 ml of a solution of 3-nitro-4-methylaminopyridine (1.5 g) in ethanol. The mixture was stirred under a hydrogen atmosphere at room temperature for 7.5 hours. Platinum oxide was removed by filtration, and the filtrate was concentrated. Thus, 962 mg (yield: 80%) of the intended product was obtained as brown crude crystals.

Aufarbeitung

  1. customPlatinum oxide was removed by filtration
  2. concentrationthe filtrate was concentrated

Quellen und Nachweise

ORD-Eintrag
ord-484ff4d8aee143319be9cb8ee8336d05
Quelldatensatz
uspto-grants-1993_11
Patentnummer
US05262415

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