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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 258322Erstellt: 24. Oktober 2026

Formaldehyde → Dimethyl alpha-hydroxymethyl-alpha-fluoromalonate

https://huagongshe.com/de/reaction/258322

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktFormaldehydeHCID 712—
EduktDimethyl fluoromalonateHCID 2737111—
ProduktDimethyl alpha-hydroxymethyl-alpha-fluoromalonateHCID 10910147—

Reaktionsschritte

The process according to the invention is carried out in three stages: dimethyl α-fluoromalonate is first reacted with formaldehyde to give dimethyl α-hydroxymethyl-α-fluoromalonate, the latter is then hydrolyzed and the hydrolysis product is decarboxylated and dehydrated, and finally, the resuiting α-fluoroacrylic acid is esterified with a substituted phenol.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05266668
Quelldatensatzuspto-grants-1993_11
ORD IDord-2656d61cbb624db69f1b75b0d589929b
Quellennotizuspto-grants-1993_11