Formaldehyde → Dimethyl alpha-hydroxymethyl-alpha-fluoromalonate

HRID 258322

Reaktionsgleichung

Reaktionsgleichung von HRID 258322
[F:1][CH:2]([C:7]([O:9][CH3:10])=[O:8])[C:3]([O:5][CH3:6])=[O:4].[CH2:11]=[O:12]>>[OH:12][CH2:11][C:2]([F:1])([C:7]([O:9][CH3:10])=[O:8])[C:3]([O:5][CH3:6])=[O:4]

Komponenten

3

Versuchsvorschrift

The process according to the invention is carried out in three stages: dimethyl α-fluoromalonate is first reacted with formaldehyde to give dimethyl α-hydroxymethyl-α-fluoromalonate, the latter is then hydrolyzed and the hydrolysis product is decarboxylated and dehydrated, and finally, the resuiting α-fluoroacrylic acid is esterified with a substituted phenol.

Quellen und Nachweise

ORD-Eintrag
ord-2656d61cbb624db69f1b75b0d589929b
Quelldatensatz
uspto-grants-1993_11
Patentnummer
US05266668

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