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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 258342Erstellt: 23. Oktober 2026

2-Chlorothiophene → Methanone, (5-chloro-2-thienyl)phenyl-

https://huagongshe.com/de/reaction/258342

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-ChlorothiopheneHCID 7299—
Edukt4-tert-ButylphenolHCID 7393—
EduktBenzoyl chlorideHCID 7412—
ProduktMethanone, (5-chloro-2-thienyl)phenyl-HCID 901505—
Produkt2-Benzoyl-5-(4-t-butyl-phenoxy)thiopheneHCID 19935313—

Reaktionsschritte

2-benzoyl-5-chlorothiophene was synthesized via Friedel-Crafts acylation of benzoyl chloride with 2-chlorothiophene. This was reacted under standard conditions with 4-t-butyl phenol to produce 2-benzoyl-5-(4-t-butyl-phenoxy)thiophene. It was discovered by thin layer chromatography that the displacement of the acyl chlorine proceeds completely with no side reactions. Complete nucleophilic displacement demonstrates that this reaction meets the requirements necessary for high polymer formation via a step growth reaction.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05266677
Quelldatensatzuspto-grants-1993_11
ORD IDord-7d9395336f5a4b8f89e6c8b95260e3f4
Quellennotizuspto-grants-1993_11