1-Chloro-4-acetoxynonane → 7-[N-(4-Hydroxy-(E)-2-nonenyl)methanesulfonamido]heptanoic Acid
Reaktionsgleichung
ClCCCC(OC(=O)C)CCCCC.BrCC=CC(OC(=O)C)CCCCC.C([CH:31]([CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][N:40]([CH2:45]/[CH:46]=[CH:47]/[CH:48]([O:54]C(=O)C)[CH2:49][CH2:50][CH2:51][CH2:52][CH3:53])[S:41]([CH3:44])(=[O:43])=[O:42])[C:32]([OH:34])=[O:33])C>>[OH:54][CH:48]([CH2:49][CH2:50][CH2:51][CH2:52][CH3:53])/[CH:47]=[CH:46]/[CH2:45][N:40]([CH2:39][CH2:38][CH2:37][CH2:36][CH2:35][CH2:31][C:32]([OH:34])=[O:33])[S:41]([CH3:44])(=[O:42])=[O:43]Komponenten
4
Versuchsvorschrift
The synthesis of this compound is carried out as described in Example 1 except that, in Step A, the 1-chloro-4-acetoxynonane is replaced by an equimolar amount of 1-bromo-4-acetoxy-2 -nonene (Example H). The product of Step A is thus ethyl 7-[N-(4-acetoxy-(E)-2-nonenyl)methanesulfonamido]heptanoic acid (B).