Dioctadecylamine → ethyl 4-Dioctadecylaminobutyrate

HRID 258732Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 258732
[CH2:1]([NH:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].Br[CH2:39][CH2:40][CH2:41][C:42]([O:44][CH2:45][CH3:46])=[O:43]>C1(C)C=CC=CC=1>[CH2:20]([N:19]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[CH2:39][CH2:40][CH2:41][C:42]([O:44][CH2:45][CH3:46])=[O:43])[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37]

Komponenten

4

Edukt 2

HCID 66989DioctadecylamineHCID 76300Ethyl 4-bromobutyrate

Produkt 1

HCID 20433003ethyl 4-DioctadecylaminobutyrateAusbeute 58,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

A solution of dioctadecylamine (5.2 g., 0.01 mole), ethyl 4-bromobutyrate (1.95 g., 0.01 mole) and toluene (50 ml.) is heated at reflux for sixteen hours, then cooled and concentrated in vacuo to a semi-solid oil. The oil is triturated with ethylacetate, filtered, and the filtrate washed with water, then dried (Na2SO4). Removal of the solvent gives the product as an oil (3.7 g.).

Aufarbeitung

  1. temperatureat reflux for sixteen hours
  2. temperaturecooled
  3. concentrationconcentrated in vacuo to a semi-solid oil
  4. customThe oil is triturated with ethylacetate
  5. filtrationfiltered
  6. washthe filtrate washed with water
  7. dry with materialdried (Na2SO4)
  8. customRemoval of the solvent

Quellen und Nachweise

ORD-Eintrag
ord-bb039cc302874f38956c18a87722eb24
Quelldatensatz
uspto-grants-1977_07
Patentnummer
US04034040

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