Dimethylamine → 1-(Dimethylamino)-1-octen-3-one

HRID 259229

Reaktionsgleichung

Reaktionsgleichung von HRID 259229
Cl[CH:2]=[CH:3][C:4](=[O:10])[CH2:5][CH2:6][CH2:7][CH2:8][CH3:9].[CH3:11][NH:12][CH3:13]>>[CH3:11][N:12]([CH3:13])[CH:2]=[CH:3][C:4](=[O:10])[CH2:5][CH2:6][CH2:7][CH2:8][CH3:9]

Komponenten

3

Edukt 2

HCID 674DimethylamineHCID 545149151-Chloro-1-octen-3-one

Produkt 1

HCID 545630821-(Dimethylamino)-1-octen-3-one

Versuchsvorschrift

A solution of dimethylamine (560 ml, 40% aqueous) is cooled to 5° C. 1-Chloro-1-octen-3-one (192 g) is added and the mixture stirred at room temperature for 20 min. The solution is then saturated with potassium carbonate and extracted with ether. The organic layer is washed 3 × with sat. sodium chloride solution, dried over sodium sulfate, concentrated and distilled to give the title compound, b.p. 94°-96° C./0.2mm.

Aufarbeitung

  1. extractionsaturated with potassium carbonate and extracted with ether
  2. washThe organic layer is washed 3 × with sat. sodium chloride solution
  3. dry with materialdried over sodium sulfate
  4. concentrationconcentrated
  5. distillationdistilled

Quellen und Nachweise

ORD-Eintrag
ord-da35dbdcd7f34d7eb2f0ca7e02ca73e6
Quelldatensatz
uspto-grants-1977_07
Patentnummer
US04036856

Verknüpfte Notizen

Wird geladen…