Piperidine → HCID 20312200, Verbindung
Reaktionsgleichung
[CH2:1]([NH:11][C:12](=[O:16])[CH2:13][C:14]#[N:15])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[CH3:17][C:18](=O)[CH2:19][C:20](=O)[CH3:21].N1CCCCC1>>[CH2:1]([N:11]1[C:18]([CH3:17])=[CH:19][C:20]([CH3:21])=[C:13]([C:14]#[N:15])[C:12]1=[O:16])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]Komponenten
4
Versuchsvorschrift
A mixture of N-(n-decyl)cyanoacetamide (93.4 g., 0.417 mole), 2.4-pentanedione (41.7 g., 0.417 mole), piperidine (8 ml.) and 2 B-ethanol (500 ml.) is stirred and refluxed for 17 hours. The mixture is cooled in an ice bath and the solid which crystallizes out is collected by filtration to give 1-(n-decyl)-3-cyano-4,6-dimethylpyrid-2-one, 95.2 g. mp. 82°-83° C.
Aufarbeitung
- temperaturerefluxed for 17 hours
- temperatureThe mixture is cooled in an ice bath