Sodium Hydroxide → N,N-Dibenzyl-L-phenylalanine

HRID 259827Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 259827
Cl.[CH2:2]([N:9]([CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[C@H:10]([C:18]([OH:20])=[O:19])[CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[OH-].[Na+]>C(Cl)Cl>[CH2:21]([N:9]([CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1)[C@H:10]([C:18]([OH:20])=[O:19])[CH2:11][C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)[C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1

Komponenten

4

Edukt 2

HCID 14798Sodium HydroxideHCID 69745698HCID 69745698, Verbindung

Produkt 1

HCID 10980880N,N-Dibenzyl-L-phenylalanine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

N,N-Dibenzyl-L-phenylalanine hydrochloride (50 g) was dissolved in methylene chloride (500 ml), and an aqueous solution of sodium hydroxide (sodium hydroxide 6 g, water 500 ml) was added thereto. After stirring the mixture for 30 minutes, it was partitioned, and the organic layer was dried over magnesium sulfate and concentrated under reduced pressure to give N,N-dibenzyl-L-phenylalanine as an oily substance.

Aufarbeitung

  1. customit was partitioned
  2. dry with materialthe organic layer was dried over magnesium sulfate
  3. concentrationconcentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-5bd915c8abba4ef192747210afc6e22e
Quelldatensatz
uspto-grants-1996_06
Patentnummer
US05523410

Notizen zur Reaktion

Wird geladen…