2,4-Dihydroxybenzoic Acid → 2-(3,4-dihydroxybenzoyl)oxymethyl-5-hydroxy-4H-pyran-4-one
Reaktionsgleichung
O[C:2]1[CH:10]=[C:9]([OH:11])[CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[OH-:12].[Na+].[CH:14]1[C:19](=[O:20])[C:18]([OH:21])=[CH:17][O:16][C:15]=1[CH2:22]Cl>>[OH:12][C:10]1[CH:2]=[C:3]([CH:7]=[CH:8][C:9]=1[OH:11])[C:4]([O:6][CH2:22][C:15]1[O:16][CH:17]=[C:18]([OH:21])[C:19](=[O:20])[CH:14]=1)=[O:5]Komponenten
4
Versuchsvorschrift
By following the procedure of Example 1 by employing 4.22 g(27.4 mmole) of 2,4-dihydroxybenzoic acid, 1.1 g (27.5 mmole) of sodium hydroxide and 4 g(24.9 mmole) of chlorokojic acid, there was obtained 5.7 g(85.3%) of 2-(3,4-dihydroxybenzoyl)oxymethyl-5-hydroxy-4H-pyran-4-one as a solid.
Quellen und Nachweise
- ORD-Eintrag