HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Pyridine → 2-Pyrrolidinone, 3-hydroxy-1-methyl-5-(3-pyridinyl)-
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Pyridine | HCID 1049 | — |
| Edukt | 3'-Hydroxycotinine, trans- | HCID 107963 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Lösungsmittel | Succinic anhydride | HCID 7922 | — |
| Produkt | 2-Pyrrolidinone, 3-hydroxy-1-methyl-5-(3-pyridinyl)- | HCID 414 | — |
Reaktionsschritte
Hydroxycotinine hemisuccinate was prepared as follows. In a glass tube, 19 mg of trans-3'-hydroxycotinine were dissolved in 1 ml of DMF. In this solution 21 mg of succinic anhydride were dissolved. After adding 20 μl of pyridine, the tube was covered (PARAFILM®) and incubated overnight at 37° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05527686 |
| Quelldatensatz | uspto-grants-1996_06 |
| ORD ID | ord-75f5640dafa64d76af267b510fdfec74 |
| Quellennotiz | uspto-grants-1996_06 |