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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 260251Erstellt: 26. Oktober 2026

Pyridine → 2-Pyrrolidinone, 3-hydroxy-1-methyl-5-(3-pyridinyl)-

https://huagongshe.com/reaction/260251

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktPyridineHCID 1049—
Edukt3'-Hydroxycotinine, trans-HCID 107963—
LösungsmittelDimethylformamideHCID 6228—
LösungsmittelSuccinic anhydrideHCID 7922—
Produkt2-Pyrrolidinone, 3-hydroxy-1-methyl-5-(3-pyridinyl)-HCID 414—

Reaktionsschritte

Hydroxycotinine hemisuccinate was prepared as follows. In a glass tube, 19 mg of trans-3'-hydroxycotinine were dissolved in 1 ml of DMF. In this solution 21 mg of succinic anhydride were dissolved. After adding 20 μl of pyridine, the tube was covered (PARAFILM®) and incubated overnight at 37° C.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05527686
Quelldatensatzuspto-grants-1996_06
ORD IDord-75f5640dafa64d76af267b510fdfec74
Quellennotizuspto-grants-1996_06