Phosphorus oxychloride → 2-(2,6-Diethyl-3-methylanilino)-2-imidazoline

HRID 260383

Reaktionsgleichung

[CH2:1]([C:3]1[C:9]([CH3:10])=[CH:8][CH:7]=[C:6]([CH2:11][CH3:12])[C:4]=1[NH2:5])[CH3:2].C([N:16]1[CH2:20][CH2:19][NH:18][C:17]1=O)(=O)C.O=P(Cl)(Cl)Cl>>[CH2:1]([C:3]1[C:9]([CH3:10])=[CH:8][CH:7]=[C:6]([CH2:11][CH3:12])[C:4]=1[NH:5][C:17]1[NH:18][CH2:19][CH2:20][N:16]=1)[CH3:2]

Komponenten

Edukt 3

HCID 24813Phosphorus oxychloride

HCID 79350N-Acetylimidazolidinone

HCID 144235m-Toluidine, 2,6-diethyl-

Produkt 1

HCID 224015932-(2,6-Diethyl-3-methylanilino)-2-imidazoline

Versuchsvorschrift

2,6-Diethyl-3-methyl aniline is reacted with N-acetyl-2-imidazolidinone in the presence of POCl3 to produce the imidazoline. This intermediate is treated with sodium hydroxide and water to remove the acetyl group and yield the name compound (VI).

Quellen und Nachweise

ORD-Eintrag: ord-269305ddd5f9418ea022ac43d34bd89e
Quelldatensatz: uspto-grants-1996_06
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US05527830

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