Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Ethanol | HCID 702 | — |
| Edukt | Flurbiprofen | HCID 3394 | — |
| Produkt | Ibuprofen, (+-)- | HCID 3672 | — |
Reaktionsschritte
Three grams of flurbiprofen and 30 g of poloxamer 237 were heated at 110° C. for 10 minutes to obtain a liquified mixture and cooled to 60° C. Into this mixture, 5 g of polyethylene glycol 300, 10 g of ethanol and 52 g of pH 4 buffer solution were added at 60° C. to obtain an ibuprofen gel.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US05527832 |
|---|
| Quelldatensatz | uspto-grants-1996_06 |
|---|
| ORD ID | ord-b0ad4fad120e4b30b6d002e81134c3db |
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| Quellennotiz | uspto-grants-1996_06 |
|---|
