Isobutylbenzene → 4'-Isobutylpentanophenone

HRID 260823Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 260823
[C:1](Cl)(=[O:6])[CH2:2][CH2:3][CH2:4][CH3:5].[Cl-].[Al+3].[Cl-].[Cl-].[CH2:12]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[CH:13]([CH3:15])[CH3:14]>ClCCl>[CH2:12]([C:16]1[CH:21]=[CH:20][C:19]([C:1](=[O:6])[CH2:2][CH2:3][CH2:4][CH3:5])=[CH:18][CH:17]=1)[CH:13]([CH3:15])[CH3:14]

Komponenten

5

Edukt 3

HCID 10870IsobutylbenzeneHCID 61186Valeryl chlorideHCID 6451240Aluminum(III) Chloride

Produkt 1

HCID 109984904'-Isobutylpentanophenone

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Reaktionsbedingungen

Temperatur
0 °C

Versuchsvorschrift

A mixture of valeryl chloride and aluminium chloride in dichloromethane was stirred at 0° C. for 30 minutes, and then isobutylbenzene was added. After stirring at 0° C. for 1 hour, the mixture was poured into ice water and extracted with dichloromethane. The organic layer was washed with an aqueous solution of sodium bicarbonate and brine, dried over magnesium sulfate and concentrated to give the object compound.

Aufarbeitung

  1. stirringAfter stirring at 0° C. for 1 hour
  2. extractionextracted with dichloromethane
  3. washThe organic layer was washed with an aqueous solution of sodium bicarbonate and brine
  4. dry with materialdried over magnesium sulfate
  5. concentrationconcentrated
  6. customto give the object compound

Quellen und Nachweise

ORD-Eintrag
ord-5ece0742f6e64f89ba2410412f18cc4f
Quelldatensatz
uspto-grants-1996_06
Patentnummer
US05530019

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