Dimethylamine → 2-(Aminomethylidene)-2,3-dihydro-1h-inden-1-one

Reaktionsgleichung

O[CH:2]=[C:3]1[CH2:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]1=[O:12].C([O-])(=O)C.[NH4+].C[NH:19]C.CN.NC(O)C>C(O)C>[NH2:19][CH:2]=[C:3]1[CH2:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]1=[O:12]

Komponenten

Edukt 5

HCID 674Dimethylamine

HCID 6329Methylamine

HCID 517165Ammonium Acetate

HCID 522583Acetaldehyde ammonia

HCID 37648821H-Inden-1-one, 2,3-dihydro-2-(hydroxymethylene)-

Produkt 1

HCID 1703122-(Aminomethylidene)-2,3-dihydro-1h-inden-1-one

Reagenzien, Katalysatoren, Lösungsmittel 1

Versuchsvorschrift

The 2-hydroxymethylene-1-indanone is then reacted with the appropriate nitrogen compound e.g. ammonium acetate, dimethyl amine, monomethyl amine or aminoethanol, in ethanol or any other suitable solvent to yield a 2-aminomethylene-1-indanone which is then dried and recrystallized from benzene or any other suitable solvent.

Quellen und Nachweise

ORD-Eintrag: ord-db4c2f4080974e02883bdad2a968ddeb
Quelldatensatz: uspto-grants-1979_08
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US04164514

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