2-Nitro-4-(trifluoromethyl)phenol → 2-Amino-4-(trifluoromethyl)phenol

HRID 261189

Reaktionsgleichung

Reaktionsgleichung von HRID 261189
[N+:1]([C:4]1[CH:9]=[C:8]([C:10]([F:13])([F:12])[F:11])[CH:7]=[CH:6][C:5]=1[OH:14])([O-])=O>C(O)C.[Pt]=O>[NH2:1][C:4]1[CH:9]=[C:8]([C:10]([F:11])([F:12])[F:13])[CH:7]=[CH:6][C:5]=1[OH:14]

Komponenten

4

Edukt 1

HCID 98162-Nitro-4-(trifluoromethyl)phenol

Produkt 1

HCID 1202462-Amino-4-(trifluoromethyl)phenol

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 82844Platinum oxide (PtO)KatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

82.2 g of 6A was dissolved in 300 ml of ethanol. 0.5 g of platinum oxide catalyst was added and the mixture was hydrogenated at 50 psig. Fresh portions of catalyst were added periodically. The reaction mixture was filtered, and the filtrate was concentrated. The residue was crystallized from water to give 2-amino-4-(trifluoromethyl)phenol (6B).

Aufarbeitung

  1. additionFresh portions of catalyst were added periodically
  2. filtrationThe reaction mixture was filtered
  3. concentrationthe filtrate was concentrated
  4. customThe residue was crystallized from water

Quellen und Nachweise

ORD-Eintrag
ord-059b6ae66e85466a99b629334c527693
Quelldatensatz
uspto-grants-1979_08
Patentnummer
US04164576

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