HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1,3-Diphenyl-2-propanone → 3,5-diphenyl-4(1H)-pyridone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1,3-Diphenyl-2-propanone | HCID 7593 | — |
| Edukt | Ethyl formate | HCID 8025 | — |
| Edukt | 2H-Pyran-2-one | HCID 68154 | — |
| Edukt | Disodium | HCID 141233 | — |
| Edukt | 3,5-diphenyl-4H-pyran-4-one | HCID 282189 | — |
| Edukt | Ammonium Acetate | HCID 517165 | — |
| Edukt | 3,4-Pentadien-2-one | HCID 10931367 | — |
| Edukt | Sodium Methoxide | HCID 10942334 | — |
| Edukt | 1,5-Dihydroxy-2,4-diphenyl-1,4-pentadien-3-one | HCID 70583784 | — |
| Produkt | 3,5-diphenyl-4(1H)-pyridone | HCID 12466680 | — |
Reaktionsschritte
The compounds of this invention can be prepared by various synthetic routes. Benary and Bitter, Ber. 61, 1058 (1928) taught the synthesis of an intermediate disodium salt of 1,5-dihydroxy-2,4-diphenyl-1,4-pentadien-3-one by the condensation of 1,3-diphenyl-2-propanone with ethyl formate in the presence of sodium methoxide. The intermediate pentadienone is neutralized by strong acid and forms 3,5-diphenyl-4-pyrone. Reaction of the pyrone with ammonium acetate at an elevated temperature produces 3,5-diphenyl-4(1H)-pyridone.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04152136 |
| Quelldatensatz | uspto-grants-1979_05 |
| ORD ID | ord-4b6acbf9a2b94c81a270b9f9ecf40673 |
| Quellennotiz | uspto-grants-1979_05 |