HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Acetic Acid → (4-chlorophenyl)(1H-imidazol-2-yl)phenylmethanol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Acetic Acid | HCID 176 | — |
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | 1-[(Benzyloxy)methyl]-alpha-(p-chlorophenyl)-alpha-phenylimidazole-2-methanol | HCID 12433915 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | (4-chlorophenyl)(1H-imidazol-2-yl)phenylmethanol | HCID 12433863 | — |
Reaktionsschritte
About 17 g. (0.042 mol) of 1-[(benzyloxy)methyl]-α-(p-chlorophenyl)-α-phenylimidazole-2-methanol was boiled under reflux in a mixture of 85 ml. of glacial acetic acid, 8.5 ml. of water and 8.5 ml. of concentrated hydrochloric acid solution. Acetic acid was removed by evaporation and the base was liberated by addition of 2 N sodium hydroxide solution. It was crystallised from isopropyl alcohol. Melting point of the product was 162°-165° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04152441 |
| Quelldatensatz | uspto-grants-1979_05 |
| ORD ID | ord-cceeaee25d9846e69e81e02792f0e7c9 |
| Quellennotiz | uspto-grants-1979_05 |