Hydrochloric Acid → 2-nitro-7-dimethylamino-6,7-dihydro [5H] benzocycloheptene hydrochloride

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Hydrochloric Acid	HCID 313	—
Edukt	Dimethylamine	HCID 674	—
Edukt	8,9-dihydro-3-nitro-5H-benzocyclohepten-5-one	HCID 20094732	—
Lösungsmittel	Ethyl Acetate	HCID 8857	—
Produkt	2-nitro-7-dimethylamino-6,7-dihydro [5H] benzocycloheptene hydrochloride	HCID 86736536	—

Reaktionsschritte

Using the procedure of Example 1, 3-nitro-8,9-dihydro [5H] benzocycloheptene-5-one and dimethylamine were reacted to obtain a non-salified product which was treated in ethyl acetate with a solution of ethyl acetate saturated with gaseous hydrogen chloride to obtain a product which was crystallized from isopropanol to obtain 2-nitro-7-dimethylamino-6,7-dihydro [5H] benzocycloheptene hydrochloride melting at 202° C.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US04154852
Quelldatensatz	uspto-grants-1979_05
ORD ID	ord-90242655c5d1464691f6d4744eae6f66
Quellennotiz	uspto-grants-1979_05