Formicin → 3-Acetamidomethylthio-2-methylpropanoic acid

HRID 262582

Reaktionsgleichung

Reaktionsgleichung von HRID 262582
[SH:1][CH2:2][CH:3]([CH3:7])[C:4]([OH:6])=[O:5].O[CH2:9][NH:10][C:11](=[O:13])[CH3:12]>FC(F)(F)C(O)=O>[C:11]([NH:10][CH2:9][S:1][CH2:2][CH:3]([CH3:7])[C:4]([OH:6])=[O:5])(=[O:13])[CH3:12]

Komponenten

4

Edukt 2

HCID 69365FormicinHCID 1529103-Mercaptoisobutyric acid

Produkt 1

HCID 213191453-Acetamidomethylthio-2-methylpropanoic acid

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6422Trifluoroacetic acidLösungsmittel

Versuchsvorschrift

3-Mercapto-2-methylpropanoic acid (2.4 g.) and N-hydroxymethylacetamide (1.8 g.) are dissolved in trifluoroacetic acid and the solution is stored at room temperature for one hour. The trifluoroacetic acid is removed in vacuo and the residue is dried in vacuo over potassium hydroxide to yield 3-acetamidomethylthio-2-methylpropanoic acid.

Aufarbeitung

  1. customThe trifluoroacetic acid is removed in vacuo
  2. dry with materialthe residue is dried in vacuo over potassium hydroxide

Quellen und Nachweise

ORD-Eintrag
ord-0608b8bc62914d75bd49bba4023019fe
Quelldatensatz
uspto-grants-1979_05
Patentnummer
US04154840

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