(Pyrazin-2-yl)methanamine → HCID 178506607, Verbindung
Reaktionsgleichung
[IH:1].[C:2](=[NH:7])(SC)[NH:3][NH2:4].[NH2:8][CH2:9][C:10]1[CH:15]=[N:14][CH:13]=[CH:12][N:11]=1>C(O)C>[IH:1].[NH2:4][NH:3][C:2]([NH:8][CH2:9][C:10]1[CH:15]=[N:14][CH:13]=[CH:12][N:11]=1)=[NH:7]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A solution of 3.66 g. of methyl thiocarbazimidate hydriodide and 3.42 g. of (aminomethyl)pyrazine [A. Hirschberg and P. Mattner, J. Med. Chem., 11, 911 (1961)] in 50 ml. of absolute ethanol is heated at reflux for 20 hours and then concentrated to dryness under reduced pressure to give the desired product as an orange solid.
Aufarbeitung
- temperatureat reflux for 20 hours
- concentrationconcentrated to dryness under reduced pressure
Quellen und Nachweise
- ORD-Eintrag
- ord-e07fb3ba6e99488eb4cea33d787f021e
- Quelldatensatz
- uspto-grants-1979_05
- Patentnummer
- US04154947
Notizen zur Reaktion
Wird geladen…