1-Bromo-3-methylbutane → 15-Methylhexadecyl bromide

HRID 262927

Reaktionsgleichung

Reaktionsgleichung von HRID 262927
[CH3:1][CH:2]([CH3:6])[CH2:3][CH2:4]Br.[Mg:7].[Br:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][Br:21]>O1CCCC1>[CH3:1][CH:2]([CH3:6])[CH2:3][CH2:4][Mg:7][Br:8].[CH3:1][CH:2]([CH3:6])[CH2:3][CH2:4][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][Br:21]

Komponenten

6

Edukt 3

HCID 78911-Bromo-3-methylbutaneHCID 187661,12-DibromododecaneHCID 5462224Magnesium

Produkt 2

HCID 2043738515-Methylhexadecyl bromideHCID 178418529HCID 178418529, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel2×

Versuchsvorschrift

A solution of 3-methylbutylmagnesium bromide is prepared by treating 15.1 g. of 3-methylbutyl bromide with 2.7 g. of magnesium turnings in 50 ml. dry tetrahydrofuran. The resultant Grignard reagent is dropwise added to a cold (-10° C.) solution of 36.1 g. of 1,12-dibromododecane and 0.2 g. of Li2CuCl4 in 75 ml. dry tetrahydrofuran. The solution is stirred for 1 hour, evaporated, and fractionally distilled in vacuo to yield 15-methylhexadecyl bromide as a colorless liquid.

Aufarbeitung

  1. additionby treating 15.1 g
  2. customevaporated
  3. distillationfractionally distilled in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-cd4c6d30f3f24615942e2a033a4ac304
Quelldatensatz
uspto-grants-1979_05
Patentnummer
US04154756

Verknüpfte Notizen

Wird geladen…