Methyl 8-methylsulfonyl-12-acetoxyheptadecanoate → 8-methylsulfonyl-12(S)-hydroxy-10-heptadecynoic acid

HRID 263008Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 263008
[CH3:1][S:2]([CH:5]([CH2:16][CH2:17][CH2:18][CH:19]([O:25]C(=O)C)[CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12]([O:14]C)=[O:13])(=[O:4])=[O:3].CS(C(CC#C[C@@H](OC(=O)C)CCCCC)CCCCCCC(OC)=O)(=O)=O>>[CH3:1][S:2]([CH:5]([CH2:16][C:17]#[C:18][C@@H:19]([OH:25])[CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13])(=[O:3])=[O:4]

Komponenten

3

Edukt 2

HCID 21317665Methyl 8-methylsulfonyl-12-acetoxyheptadecanoateHCID 22796981methyl 8-methylsulfonyl-12(S)-acetoxy-10-heptadecynoate

Produkt 1

HCID 227969758-methylsulfonyl-12(S)-hydroxy-10-heptadecynoic acid

Versuchsvorschrift

The synthesis of this compound is carried out by the method of Example 3, Step E, except that methyl 8-methylsulfonyl-12-acetoxyheptadecanoate is replaced by an equivalent quantity of methyl 8-methylsulfonyl-12(S)-acetoxy-10-heptadecynoate.

Aufarbeitung

  1. customThe synthesis of this compound

Quellen und Nachweise

ORD-Eintrag
ord-c0299b4205774664bcf048a89ab099e8
Quelldatensatz
uspto-grants-1979_05
Patentnummer
US04155908

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