Octanoyl chloride → 4-(S)-Isopropyl-3-(1-oxooctyl)-2-oxazolidinone

HRID 263446Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 263446
[CH:1]([C@H:4]1[CH2:8][O:7][C:6](=[O:9])[NH:5]1)([CH3:3])[CH3:2].[C:10](Cl)(=[O:18])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17]>>[CH:1]([C@H:4]1[CH2:8][O:7][C:6](=[O:9])[N:5]1[C:10](=[O:18])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])([CH3:3])[CH3:2]

Komponenten

3

Edukt 2

HCID 8124Octanoyl chlorideHCID 7157133(4S)-4-(propan-2-yl)-1,3-oxazolidin-2-one

Produkt 1

HCID 108486184-(S)-Isopropyl-3-(1-oxooctyl)-2-oxazolidinoneAusbeute 93,9 %

Versuchsvorschrift

Following the procedure described in Referential Example 3, but using 4-(S)-isopropyl-2-oxazolidinone (5.06 g) and octanoyl chloride (6.67 g), the desired compound (9.39 g) was obtained.

Quellen und Nachweise

ORD-Eintrag
ord-ed776518fcc4420ba8ecedb84b43ae59
Quelldatensatz
uspto-grants-1997_07
Patentnummer
US05643908

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