Diisopropylaniline → (+/-)-5-(diphenylmethyl)-alpha-phenyl-N-(2,4,6-trimethoxyphenyl)-2H-tetrazole-2-acetamide

HRID 264079

Reaktionsgleichung

Reaktionsgleichung von HRID 264079
[C:1]1([CH:7]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[C:8]2[N:9]=[N:10][N:11]([CH:13]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[C:14](O)=[O:15])[N:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C(C1N=NN(CC(O)=O)N=1)CCCCCCCCC.[CH3:48][O:49][C:50]1[CH:56]=[C:55]([O:57][CH3:58])[CH:54]=[C:53]([O:59][CH3:60])[C:51]=1[NH2:52].C(C1C=CC=C(C(C)C)C=1N)(C)C>>[C:23]1([CH:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[C:8]2[N:9]=[N:10][N:11]([CH:13]([C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=3)[C:14]([NH:52][C:51]3[C:53]([O:59][CH3:60])=[CH:54][C:55]([O:57][CH3:58])=[CH:56][C:50]=3[O:49][CH3:48])=[O:15])[N:12]=2)[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1

Komponenten

5

Edukt 4

HCID 32484DiisopropylanilineHCID 842712,4,6-TrimethoxyanilineHCID 21469485(+/-)-5-(diphenylmethyl)-alpha-phenyl-2H-tetrazole-2-acetic acidHCID 214695295-decyl-2H-tetrazole-2-acetic acid

Produkt 1

HCID 21469467(+/-)-5-(diphenylmethyl)-alpha-phenyl-N-(2,4,6-trimethoxyphenyl)-2H-tetrazole-2-acetamide

Versuchsvorschrift

When in the general procedure of Example 88 an appropriate amount of (±)-5-(diphenylmethyl)-α-phenyl-2H-tetrazole-2-acetic acid was substituted for 5-decyl-2H-tetrazole-2-acetic acid and 2,4,6-tri-methoxyaniline was substituted for 2,6-diisopropyl-aniline, the title compound was obtained, mp 114°-117° C.

Quellen und Nachweise

ORD-Eintrag
ord-498f72019ae54263bdac39241e36a473
Quelldatensatz
uspto-grants-1997_07
Patentnummer
US05646170

Verknüpfte Notizen

Wird geladen…