HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Uridine → 2'-O-Nonyluridine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Uridine | HCID 6029 | — |
| Edukt | 1-Iodononane | HCID 20275 | — |
| Edukt | Dibutyltin oxide | HCID 61221 | — |
| Edukt | 2',3'-O-dibutylstannyleneuridine | HCID 131720090 | — |
| Produkt | 2'-O-Nonyluridine | HCID 22874743 | — |
Reaktionsschritte
As per the procedure of Example 49, uridine (22.5 g) was treated with dibutyl tin oxide (22.5 g, 1 eq). The resulting 2',3'-O-dibutylstannyleneuridine was treated with iodononane (11 ml, 1.3 eq.) at 130°-140° C. as per Example 50 to give the 2' and 3' isomers (11.2 g) as an oil.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05646265 |
| Quelldatensatz | uspto-grants-1997_07 |
| ORD ID | ord-749385ee83504457b5d87e3afcdc281f |
| Quellennotiz | uspto-grants-1997_07 |