HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Cytidine → 2'-O-Propylcytidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Cytidine | HCID 6175 | — |
| Edukt | 1-Bromopropane | HCID 7840 | — |
| Edukt | Sodium hydride | HCID 24758 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 2'-O-Propylcytidine | HCID 22874746 | — |
Reaktionsschritte
Cytidine (16.5 g, 0.068 mol) was treated with sodium hydride (4.5 g) and bromopropane (15 ml) in DMF (150 ml) at room temperature for three days. The resulting reaction mixture was used directly in the next step (see Example 83).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05646265 |
| Quelldatensatz | uspto-grants-1997_07 |
| ORD ID | ord-ebe1e5446f864986a5d6bd5adfda59ed |
| Quellennotiz | uspto-grants-1997_07 |