Hippuric Acid → Azlactone

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

657 gm (3.66 mol) of hippuric acid and 2,618 gm of acetic anhydride were charged into a 5 1 glass reaction vessel, and heated at 80° C. for 15 minutes. When the reaction liquid became transparent, the reaction vessel was placed into a water bath to lower the internal temperature to 30° C., followed by cooling to 0° C. on a dry ice-methanol bath.

Herkunft & Nachweise