HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2,4,5-Triphenylimidazole → 1-(7-Bromoheptyl)-2,4,5-triphenylimidazole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2,4,5-Triphenylimidazole | HCID 10232 | — |
| Edukt | Potassium Carbonate | HCID 11430 | — |
| Edukt | 1,7-Dibromoheptane | HCID 78309 | — |
| Lösungsmittel | Methyl Ethyl Ketone | HCID 6569 | — |
| Produkt | 1-(7-Bromoheptyl)-2,4,5-triphenylimidazole | HCID 22916377 | 61,5% |
Reaktionsschritte
A mixture of 2,4,5-triphenylimidazole (11.5 g), 1,7-dibromo-heptane (50 g) and potassium carbonate (27 g) in dry butanone (250 ml) was heated at reflux for 20 hours. The mixture was filtered and the filtrate evaporated to an oil. Chromatography on silica gel (hexane/ethyl acetate) and recrystallisation from hexane gave 1-(7-bromoheptyl)-2,4,5-triphenylimidazole (11.3 g, 61.4%) as a colourless solid, m.p. 69°-71°.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05648373 |
| Quelldatensatz | uspto-grants-1997_07 |
| ORD ID | ord-20d0f6ec73f5498fbde81cc099d2687a |
| Quellennotiz | uspto-grants-1997_07 |