Hydrochloric Acid → 4-(2-Pyrrolidin-1-yl-ethoxy)-benzoic acid
Reaktionsgleichung
[N:1]1([CH2:6][CH2:7][O:8][C:9]2[CH:18]=[CH:17][C:12]([C:13]([O:15]C)=[O:14])=[CH:11][CH:10]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1.Cl>>[N:1]1([CH2:6][CH2:7][O:8][C:9]2[CH:10]=[CH:11][C:12]([C:13]([OH:15])=[O:14])=[CH:17][CH:18]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1Komponenten
3
Versuchsvorschrift
Compound 27-6 (1.5 g, 6.0 mmol) was treated with 6N HCl for 48 hours at room temperature and 60° C. for 2 hours. The solvent was removed to give 27-7 as a white solid.
Aufarbeitung
- customThe solvent was removed
Quellen und Nachweise
- ORD-Eintrag
- ord-b8adc378d9c94cd4969665ed965d3496
- Quelldatensatz
- uspto-grants-1997_07
- Patentnummer
- US05648368
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