Dicyclohexylcarbodiimide → 2-Dimethylaminopyridine

HRID 266179Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 266179
[CH3:1][C@H]1OC(=O)C2C(O)=CC(O)=C(Cl)C=2CC(=O)C=CC=C[C@H]2O[C@H]2C1.C(O)(=O)C#CCCCCC.[CH:36]1([N:42]=[C:43]=[N:44][CH:45]2[CH2:50][CH2:49][CH2:48]CC2)CCCCC1>O1CCCC1>[CH3:1][N:42]([C:43]1[CH:48]=[CH:49][CH:50]=[CH:45][N:44]=1)[CH3:36]

Komponenten

5

Edukt 3

HCID 10868DicyclohexylcarbodiimideHCID 218722-Octynoic acidHCID 11268547CID 11268547

Produkt 1

HCID 218852-Dimethylaminopyridine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

Following a procedure similar to that described in Example 12, but using 730 mg of radicicol, 701 mg of 2-octynoic acid, 15 ml of dry tetrahydrofuran, 1.03 g of dicyclohexylcarbodiimide and a catalytic amount of dimethylaminopyridine, 611 mg of the title compound were obtained.

Quellen und Nachweise

ORD-Eintrag
ord-09688a08f58240fc91fe5d29d21e9e1f
Quelldatensatz
uspto-grants-1997_07
Patentnummer
US05650430

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