HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 266698Erstellt: 26. Oktober 2026
Ethylene Oxide → 1-(2-Hydroxyethyl)-4-(N-propionylanilino)piperidine
https://huagongshe.com/reaction/266698
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Ethylene Oxide | HCID 6354 | — |
| Edukt | 4-(N-Propionylaniline)piperidine | HCID 259381 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Lösungsmittel | Toluene | HCID 1140 | — |
| Produkt | 1-(2-Hydroxyethyl)-4-(N-propionylanilino)piperidine | HCID 10850080 | — |
Reaktionsschritte
A solution, cooled to 15° C., containing 100 mmol of ethylene oxide in toluene is added slowly to 100 mmol of 4-(N-propionylanilino)piperidine in solution in 100 ml of anhydrous methanol cooled to 15° C. After returning to room temperature and removal of the azeotrope formed by distillation, the expected product is obtained after evaporation to dryness.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patentnummer | US05652246 |
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| Quelldatensatz | uspto-grants-1997_07 |
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| ORD ID | ord-0cf41979ba5f46fc9d1a0f479f4905b6 |
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| Quellennotiz | uspto-grants-1997_07 |
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