Acetone → Methyl 4-acetyl-3-methylphenoxyacetate

HRID 266735

Reaktionsgleichung

Reaktionsgleichung von HRID 266735
[CH3:1][C:2]1[CH:7]=[C:6]([OH:8])[CH:5]=[CH:4][C:3]=1[C:9]([CH3:11])=[O:10].[C:12](=O)([O-])[O-:13].[K+].[K+].C[C:19]([CH3:21])=[O:20]>>[C:9]([C:3]1[CH:4]=[CH:5][C:6]([O:8][CH2:21][C:19]([O:13][CH3:12])=[O:20])=[CH:7][C:2]=1[CH3:1])(=[O:10])[CH3:11]

Komponenten

4

Edukt 3

HCID 180AcetoneHCID 11430Potassium CarbonateHCID 701334-Hydroxy-2-methylacetophenone

Produkt 1

HCID 18918401Methyl 4-acetyl-3-methylphenoxyacetate

Versuchsvorschrift

A mixture of 4-hydroxy-2-methylacetophenone (4.8 g), anhydrous potassium carbonate (5.3 g) and methyl brDmoacetate (3.55 ml) in anhydrous acetone (100 ml) was stirred for 2 days. The mixture, after filtration and evaporation of the solvent, gave methyl 4-acetyl-3-methylphenoxyacetate, 6.6 g, as a crystalline solid: m.p. 49°-50° C.; NMR (d6DMSO) δ 7.84 (1H, d), 6.83 (2H, m), 4.87 (2H, s), 3.71 (3H, s), 2.50 (3H, s), 2.45 (3H, s).

Aufarbeitung

  1. filtrationThe mixture, after filtration and evaporation of the solvent

Quellen und Nachweise

ORD-Eintrag
ord-905a2284465946e2a4495f7b48209b3b
Quelldatensatz
uspto-grants-1997_07
Patentnummer
US05652242

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