HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Propargyl bromide → 7-(2-Propyn-1-yloxy)-2H-1-benzopyran-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Propargyl bromide | HCID 7842 | — |
| Edukt | Potassium Carbonate | HCID 11430 | — |
| Edukt | Umbelliferone | HCID 5281426 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 7-(2-Propyn-1-yloxy)-2H-1-benzopyran-2-one | HCID 3051101 | 60% |
Reaktionsschritte
In 100 ml DMF at 70° C. for 12 hours, 0.1 mole 7-hydroxy-coumarin is reacted with 0.1 mole propargyl bromide in the presence of 0.1 mole potassium carbonate. The compound of the title is obtained at a 60% yield. This compound melts at 118° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04151291 |
| Quelldatensatz | uspto-grants-1979_04 |
| ORD ID | ord-65bf7f0d4bdc4cc0983572099323cd68 |
| Quellennotiz | uspto-grants-1979_04 |