Benzenamine, 2-chloro-5-(trifluoromethyl)- → N-(2,2-dicyanovinyl)-2-chloro-5-trifluoromethylaniline

HRID 26707

Reaktionsgleichung

Reaktionsgleichung von HRID 26707
[Cl:1][C:2]1[CH:8]=[CH:7][C:6]([C:9]([F:12])([F:11])[F:10])=[CH:5][C:3]=1[NH2:4].C(O[CH:16]=[C:17]([C:20]#[N:21])[C:18]#[N:19])C>C(O)C>[C:18]([C:17]([C:20]#[N:21])=[CH:16][NH:4][C:3]1[CH:5]=[C:6]([C:9]([F:10])([F:11])[F:12])[CH:7]=[CH:8][C:2]=1[Cl:1])#[N:19]

Komponenten

4

Edukt 2

HCID 8475Benzenamine, 2-chloro-5-(trifluoromethyl)-HCID 671522-(Ethoxymethylene)propanedinitrile

Produkt 1

HCID 21322397N-(2,2-dicyanovinyl)-2-chloro-5-trifluoromethylanilineAusbeute 70 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

19.6 Parts of 2-chloro-5-trifluoromethyl-aniline and 12.2 parts of ethoxymethylenemalononitrile are dissolved in 125 parts of ethanol and the mixture is refluxed for 48 hours. After cooling, the precipitated product is collected by filtration and washed with ethanol. Recrystallisation from ethanol affords the above product with a melting point of 166°-169° C. and in a 70% yield.

Aufarbeitung

  1. temperaturethe mixture is refluxed for 48 hours
  2. temperatureAfter cooling
  3. filtrationthe precipitated product is collected by filtration
  4. washwashed with ethanol
  5. customRecrystallisation from ethanol
  6. customaffords the above product with a melting point of 166°-169° C.

Quellen und Nachweise

ORD-Eintrag
ord-bc92207860594f63ba30a4e98edc8c79
Quelldatensatz
uspto-grants-1979_04
Patentnummer
US04151298

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