Sodium Hydroxide → N-Acetyl-L-phenylalanine

Beteiligte Stoffe

Reaktionsschritte

To 310 parts by volume of an aqueous 0.5N sodium hydroxide solution, heated to about 70°, is added, successively, 17.7 parts of N-acetyl-L-phenylalanine and 33.3 parts of DL-phenylalanine methyl ester hydrochloride. A precipitate forms and upon cooling and filtering, the salt of N-acetyl-L-phenylalanine and D-phenylalanine methyl ester is obtained. Recrystallization from hot water affords the pure salt exhibiting an [α]D in 0.5% water of about +32.2°.

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