2,6-Diethylaniline → N-(1,3-dioxolan-2-ylmethyl)-2,6-diethylaniline

HRID 267456

Reaktionsgleichung

Reaktionsgleichung von HRID 267456
[CH2:1]([C:3]1[CH:9]=[CH:8][CH:7]=[C:6]([CH2:10][CH3:11])[C:4]=1[NH2:5])[CH3:2].Cl[CH2:13][CH:14]1[O:18][CH2:17][CH2:16][O:15]1.C(=O)([O-])[O-].[K+].[K+]>CN(C)C=O>[O:15]1[CH2:16][CH2:17][O:18][CH:14]1[CH2:13][NH:5][C:4]1[C:6]([CH2:10][CH3:11])=[CH:7][CH:8]=[CH:9][C:3]=1[CH2:1][CH3:2]

Komponenten

5

Edukt 3

HCID 113692,6-DiethylanilineHCID 11430Potassium CarbonateHCID 757272-(Chloromethyl)-1,3-dioxolane

Produkt 1

HCID 21548997N-(1,3-dioxolan-2-ylmethyl)-2,6-diethylaniline

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6228DimethylformamideLösungsmittel

Versuchsvorschrift

2,6-Diethylaniline (75 grams; 0.5 mole), 2-chloromethyl-1,3-dioxolane (25 grams; 0.2 mole), potassium carbonate (22 grams; 0.2 mole) and dimethylformamide (50 ml) were charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. The reaction mixture was heated, with stirring, for a period of about 18 hours. After this time the reaction mixture was filtered and then distilled to yield the desired product N-(1,3-dioxolan-2-ylmethyl)-2,6-diethylaniline.

Aufarbeitung

  1. customequipped with a mechanical stirrer
  2. temperaturethermometer and reflux condenser
  3. temperatureThe reaction mixture was heated
  4. filtrationAfter this time the reaction mixture was filtered
  5. distillationdistilled

Quellen und Nachweise

ORD-Eintrag
ord-df9390a986484d88b6fc2cd9ef6aee01
Quelldatensatz
uspto-grants-1976_03
Patentnummer
US03942972

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