Sodium Diethyldithiocarbamate → 2-Amino-5-cyano-6-diethylthiocarbamylthio-1-n-octyl-4-n-octylamino pyridinium chloride

HRID 267735

Reaktionsgleichung

Reaktionsgleichung von HRID 267735
[Cl-].[NH2:2][C:3]1[CH:8]=[C:7]([NH:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[C:6]([C:18]#[N:19])=[C:5]([Cl:20])[N+:4]=1[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28].[CH2:29]([N:31]([CH2:35][CH3:36])[C:32](=[S:34])[S-:33])[CH3:30].[Na+]>CN(C)C=O>[Cl-:20].[NH2:2][C:3]1[CH:8]=[C:7]([NH:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[C:6]([C:18]#[N:19])=[C:5]([S:34][C:32](=[S:33])[N:31]([CH2:35][CH3:36])[CH2:29][CH3:30])[N+:4]=1[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]

Komponenten

4

Edukt 2

HCID 533728Sodium DiethyldithiocarbamateHCID 122967422-Amino-6-chloro-5-cyano-1-n-octyl-4-n-octylamino pyridinium chloride

Produkt 1

HCID 867331562-Amino-5-cyano-6-diethylthiocarbamylthio-1-n-octyl-4-n-octylamino pyridinium chlorideAusbeute 30 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6228DimethylformamideLösungsmittel

Versuchsvorschrift

4.5 gms (.01 mole) of 2-amino-6-chloro-5-cyano-1-n-octyl-4-n-octylamino pyridinium chloride (compound 14 - Table 1) was dissolved in dimethylformamide and 2.2 gms (0.01 mole) of sodium diethyldithiocarbamate added and the solution refluxed for 60 minutes. This was then cooled, filtered and the solvent evaporated off. Methanol was added and 1.6 gms (30% yield) of 2-amino-5-cyano-6-diethylthiocarbamylthio-1-n-octyl-4-n-octylamino pyridinium chloride (compound 80 - Table 5) was filtered off and recrystallised from methanol (MPt 124° - 126°C.)

Aufarbeitung

  1. temperaturethe solution refluxed for 60 minutes
  2. temperatureThis was then cooled
  3. filtrationfiltered
  4. customthe solvent evaporated off
  5. additionMethanol was added

Quellen und Nachweise

ORD-Eintrag
ord-1c92f00fecb54eda8c52435663db76a2
Quelldatensatz
uspto-grants-1976_03
Patentnummer
US03944557

Verknüpfte Notizen

Wird geladen…