Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Sulfuric Acid | HCID 1118 | — |
| Edukt | 3-Chloro-1-(4-fluorophenyl)-2-methylpropan-1-one | HCID 21521890 | — |
| Produkt | 5-Fluoro-2-methylindan-1-one | HCID 3016257 | — |
Reaktionsschritte
Ten grams (0.05 mole) of 3-chloro-4'-fluoro-2-methylpropiophenone is added to 20 ml. of concentrated sulfuric acid at 20°-25°C and the mixture is warmed to 50°C. After stirring for three hours at 50°C, the reaction is quenched in ice. The product is extracted into hexane. The hexane layer is concentrated in vacuo to give 5-fluoro-2-methyl-1-indanone.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US03944600 |
|---|
| Quelldatensatz | uspto-grants-1976_03 |
|---|
| ORD ID | ord-ef9548ffde9840f3976ff426f25eaccf |
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| Quellennotiz | uspto-grants-1976_03 |
|---|
