4-Nitrophenyl trifluoroacetate → HCID 178524480, Verbindung

HRID 267900

Reaktionsgleichung

Reaktionsgleichung von HRID 267900
[OH:1][C:2]1[N:3]=[N:4][CH:5]=[CH:6][C:7]=1[C:8]([OH:10])=[O:9].FC(F)(F)C(O[C:16]1[CH:21]=[CH:20][C:19]([N+:22]([O-:24])=[O:23])=[CH:18][CH:17]=1)=O>N1C=CC=CC=1>[OH:1][C:2]1[N:3]=[N:4][CH:5]=[CH:6][C:7]=1[C:8]([O:10][C:16]1[CH:21]=[CH:20][C:19]([N+:22]([O-:24])=[O:23])=[CH:18][CH:17]=1)=[O:9]

Komponenten

4

Edukt 2

HCID 695694-Nitrophenyl trifluoroacetateHCID 178524569HCID 178524569, Verbindung

Produkt 1

HCID 178524480HCID 178524480, VerbindungAusbeute 84,7 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1049PyridineLösungsmittel

Versuchsvorschrift

3-Hydroxypyridazine-4-carboxylic acid (1.40 g) was dissolved in pyridine (20 ml) at 40°C, and p-nitrophenyl trifluoroacetate (2.82 g) was dropwise added thereto. The resultant mixture was stirred at 40° to 50°C for 1 hour and concentrated under reduced pressure to dryness. The residue was washed with chloroform and acetone in order and dried to give the objective compound (2.21 g). M.P. 233°C (decomp.).

Aufarbeitung

  1. concentrationconcentrated under reduced pressure to dryness
  2. washThe residue was washed with chloroform and acetone in order
  3. customdried

Quellen und Nachweise

ORD-Eintrag
ord-8732018f8a8e449eb7f5aeb7d2f1c1fb
Quelldatensatz
uspto-grants-1976_03
Patentnummer
US03945995

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