HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1,3-Cyclohexanedione → 2-Amino-4-(biphenyl-2-yl)-1,4,5,6,7,8-hexahydro-5-oxoquinoline-3-carboxylic acid ethyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1,3-Cyclohexanedione | HCID 10434 | — |
| Edukt | (1,1'-Biphenyl)-2-carboxaldehyde | HCID 121052 | — |
| Edukt | Carbamimidoyl-acetic acid ethyl ester | HCID 4599837 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 2-Amino-4-(biphenyl-2-yl)-1,4,5,6,7,8-hexahydro-5-oxoquinoline-3-carboxylic acid ethyl ester | HCID 12391115 | 45% |
Reaktionsschritte
Upon heating a solution of 6.1 g of biphenyl-2-aldehyde, 3.8 g of cyclohexane-1,3-dione and 5.1 g of amidinoacetic acid ethyl ester in 100 ml of ethanol for 1 hour, 2-amino-4-(biphenyl-2-yl)-1,4,5,6,7,8-hexahydro-5-oxoquinoline-3-carboxylic acid ethyl ester of melting point 248°C (ethanol) is obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US03946026 |
| Quelldatensatz | uspto-grants-1976_03 |
| ORD ID | ord-80556131a437473c9cbb2b539be94f07 |
| Quellennotiz | uspto-grants-1976_03 |