4-Methyl-3-nitroaniline → HCID 178428208, Verbindung

HRID 268274

Reaktionsgleichung

Reaktionsgleichung von HRID 268274
[ClH:1].N([C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[C:16]3[N:21]=[CH:20][NH:19][C:17]3=2)[N:12]=[C:11]([CH3:22])[CH:10]=1)C1C=CC=CC=1.[CH3:23][C:24]1[CH:30]=[CH:29][C:27]([NH2:28])=[CH:26][C:25]=1[N+:31]([O-:33])=[O:32]>C(O)C>[ClH:1].[CH3:23][C:24]1[CH:30]=[CH:29][C:27]([NH:28][C:9]2[C:18]3[C:13](=[CH:14][CH:15]=[C:16]4[N:21]=[CH:20][NH:19][C:17]4=3)[N:12]=[C:11]([CH3:22])[CH:10]=2)=[CH:26][C:25]=1[N+:31]([O-:33])=[O:32]

Komponenten

4

Edukt 2

HCID 83904-Methyl-3-nitroanilineHCID 178428198HCID 178428198, Verbindung

Produkt 1

HCID 178428208HCID 178428208, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A mixture of 10.85 g. (0.05 m.) of the compound of Example I, C., 7.6 g. (0.05 m.) of 4-methyl-3-nitroaniline and 500 ml. of ethanol was refluxed overnight. The reaction mixture was concentrated in vacuo to give 38 g. of crude product. It was then dissolved in 6000 ml. of MeOH and filtered hot. The MeOH filtrate was concentrated in vacuo to yield 27 g., m.p. 344°-345°C.

Aufarbeitung

  1. additionA mixture of 10.85 g
  2. concentrationThe reaction mixture was concentrated in vacuo
  3. customto give 38 g
  4. dissolutionIt was then dissolved in 6000 ml
  5. filtrationof MeOH and filtered hot
  6. concentrationThe MeOH filtrate was concentrated in vacuo
  7. customto yield 27 g

Quellen und Nachweise

ORD-Eintrag
ord-5a650ce85fff40e790f052503055eb84
Quelldatensatz
uspto-grants-1976_03
Patentnummer
US03947434

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