Ethanol → (1-Ethyl-1H-1,2,4-triazol-5-yl)methylammonium acetate

HRID 268598Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 268598
[CH2:1]([N:3]1[C:7]([CH:8]=[N:9][OH:10])=[N:6][CH:5]=[N:4]1)[CH3:2].[CH2:11]([OH:13])[CH3:12]>[OH-].[OH-].[Pd+2]>[C:11]([O-:10])(=[O:13])[CH3:12].[CH2:1]([N:3]1[C:7]([CH2:8][NH3+:9])=[N:6][CH:5]=[N:4]1)[CH3:2]

Komponenten

4

Edukt 2

HCID 702EthanolHCID 136335088HCID 136335088, Verbindung

Produkt 1

HCID 86603337(1-Ethyl-1H-1,2,4-triazol-5-yl)methylammonium acetate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 9942167Palladium hydroxideKatalysator

Versuchsvorschrift

A mixture of 1-ethyl-1H-1,2,4-triazole-5-carbaldehyde oxime (6.17 g, 44 mmol), 10% palladium hydroxide on carbon (2.9 g) acetic acid (125 mL) and ethanol (125 mL) were stirred under an atmosphere of hydrogen for 14 hours. The reaction mixture was filtered and concentrated in vacuo to give the title compound (7.7 g) 1H-NMR (d6-DMSO) δ 1.32 (3H, t, J=7 Hz), 1.89 (3H, s), 3.89 (2H, br), 4.17 (2H, q, J=7 Hz), 7.80 (1H, s).

Aufarbeitung

  1. filtrationThe reaction mixture was filtered
  2. concentrationconcentrated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-bab6cf9741d448c0be083d102f1aedc7
Quelldatensatz
uspto-grants-2008_11
Patentnummer
US07446117B2

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