Methyl Isocyanate → N-Methyl-N'-[2-(3-pyridazinylmethylamino)ethyl]urea

Reaktionsgleichung

[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][NH:8][CH2:9][CH2:10][NH2:11])[N:2]=1.[CH3:12][N:13]=[C:14]=[O:15]>>[CH3:12][NH:13][C:14]([NH:11][CH2:10][CH2:9][NH:8][CH2:7][C:3]1[N:2]=[N:1][CH:6]=[CH:5][CH:4]=1)=[O:15]

Komponenten

Edukt 2

HCID 12228Methyl Isocyanate

HCID 21698444N-(3-pyridazinylmethyl)ethylenediamine

Produkt 1

HCID 20557601N-Methyl-N'-[2-(3-pyridazinylmethylamino)ethyl]urea

Versuchsvorschrift

Reacting N-(3-pyridazinylmethyl)ethylenediamine with methyl isocyanate by the procedure of Example 24, then concentrating and separating the residue by column chromatography gives the title compound.

Aufarbeitung

concentrationconcentrating
customseparating the residue by column chromatography

Quellen und Nachweise

ORD-Eintrag: ord-37d0fd6b8ba442f98ecc91c758c00a2a
Quelldatensatz: uspto-grants-1979_04
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US04151288

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