3-(1H-Indol-6-yl)-3-(2-methoxy-phenyl)-N-methyl-propionamide → HCID 59831880, Verbindung
Reaktionsgleichung
CO[C:3](=[O:22])[CH2:4][CH:5]([C:13]1[CH:21]=[C:20]2[C:16]([CH:17]=[CH:18][NH:19]2)=[CH:15][CH:14]=1)[C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([Cl:12])[CH:7]=1.[NH:23]1C2C(=CC=C(C(C3C=CC=CC=3OC)CC(NC)=O)C=2)C=[CH:24]1>>[NH:19]1[C:20]2[C:16](=[CH:15][CH:14]=[C:13]([CH:5]([C:6]3[CH:11]=[CH:10][CH:9]=[C:8]([Cl:12])[CH:7]=3)[CH2:4][C:3]([NH:23][CH3:24])=[O:22])[CH:21]=2)[CH:17]=[CH:18]1Komponenten
3
Versuchsvorschrift
3-(1H-Indol-6-yl)-3-(3-chloro-phenyl)-N-methyl-propionamide XLI (340 mg, 89% yield) was prepared from 3-(1H-indol-6-yl)-3-(3-chloro-phenyl)-propionic acid methyl ester using the procedure described above for 3-(1H-Indol-6-yl)-3-(2-methoxy-phenyl)-N-methyl-propionamide XXXVIII (see Example 9).
Quellen und Nachweise
- ORD-Eintrag
- ord-c215c2438ffa4f8c9c09e6dfa2f1eb3e
- Quelldatensatz
- uspto-grants-2008_11
- DOI