HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(4-Benzyloxy-3-chlorophenyl)-4-(3-cyclohexylpropyl)piperazine → 4-[4-[2-(4-Chlorophenyl)-ethyl]piperazin-1-yl]-2-fluorophenol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(4-Benzyloxy-3-chlorophenyl)-4-(3-cyclohexylpropyl)piperazine | HCID 23111408 | — |
| Edukt | 1-(4-Benzyloxy-3-fluorophenyl)-4-[2-(4-chlorophenyl)-ethyl]piperazine | HCID 23111471 | — |
| Produkt | 4-[4-[2-(4-Chlorophenyl)-ethyl]piperazin-1-yl]-2-fluorophenol | HCID 23111434 | 87,4% |
Reaktionsschritte
Production Example 30 was repeated except that 1-(4-benzyloxy-3-chlorophenyl)-4-(3-cyclohexylpropyl)piperazine was replaced with 1-(4-benzyloxy-3-fluorophenyl)-4-[2-(4-chlorophenyl)-ethyl]piperazine (373 mg), to provide crude 4-[4-[2-(4-chlorophenyl)-ethyl]piperazin-1-yl]-2-fluorophenol (257 mg).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07449466B2 |
| Quelldatensatz | uspto-grants-2008_11 |
| ORD ID | ord-6ac0f3d567ea451eb9b2e034474502fb |
| Quellennotiz | uspto-grants-2008_11 |