HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Phenethyl bromide → 1-(4-Benzyloxy-3-fluorophenyl)-4-(3-cyclopentylpropyl)piperazine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Phenethyl bromide | HCID 7666 | — |
| Edukt | 1-(4-Methoxyphenyl)-piperazine, dihydrochloride | HCID 2723700 | — |
| Edukt | 3-Cyclopentylpropyl methanesulfonate | HCID 23111435 | — |
| Edukt | 1-(4-Benzyloxy-3-fluorophenyl)piperazine | HCID 23111483 | — |
| Produkt | 1-(4-Benzyloxy-3-fluorophenyl)-4-(3-cyclopentylpropyl)piperazine | HCID 23111413 | — |
Reaktionsschritte
Production Example 1 was repeated except that 1-(4-methoxyphenyl)piperazine dihydrochloride and (2-bromoethyl)-benzene were replaced with 1-(4-benzyloxy-3-fluorophenyl)piperazine (368 mg) and 3-cyclopentylpropyl methanesulfonate (319 mg), respectively, to provide crude 1-(4-benzyloxy-3-fluorophenyl)-4-(3-cyclopentylpropyl)piperazine (505 mg).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07449466B2 |
| Quelldatensatz | uspto-grants-2008_11 |
| ORD ID | ord-b3401e26144b4c8387107b7b946ea728 |
| Quellennotiz | uspto-grants-2008_11 |