1-(4-Benzyloxy-3-chlorophenyl)-4-(3-cyclohexylpropyl)piperazine → 4-[4-(3-Cyclo-pentylpropyl)piperazin-1-yl]-2-fluorophenol hydrochloride

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	1-(4-Benzyloxy-3-chlorophenyl)-4-(3-cyclohexylpropyl)piperazine	HCID 23111408	—
Edukt	1-(4-Benzyloxy-3-fluorophenyl)-4-(3-cyclopentylpropyl)piperazine	HCID 23111413	—
Produkt	4-[4-(3-Cyclo-pentylpropyl)piperazin-1-yl]-2-fluorophenol hydrochloride	HCID 23111453	—

Reaktionsschritte

Production Example 30 was repeated except that 1-(4-benzyloxy-3-chlorophenyl)-4-(3-cyclohexylpropyl)piperazine was replaced with 1-(4-benzyloxy-3-fluorophenyl)-4-(3-cyclopentylpropyl)-piperazine (494 mg), to provide 4-[4-(3-cyclo-pentylpropyl)piperazin-1-yl]-2-fluorophenol hydrochloride (398 mg).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07449466B2
Quelldatensatz	uspto-grants-2008_11
ORD ID	ord-63c34ff4ba224e64bbb6bf7a39c8b536
Quellennotiz	uspto-grants-2008_11